Is 100mg of Testosterone
a Week Enough?

Is 100mg of Testosterone a Week Enough?

Is 100mg of testosterone a week enough? Learn about testosterone replacement therapy (TRT) and the right dosage to achieve optimal health.

Table of Contents

Introduction

Testosterone replacement therapy (TRT) is a medical treatment that involves increasing the testosterone level in the body. Testosterone is an essential hormone, and optimal levels can have numerous benefits. 

However, when it comes to TRT dosage, many people wonder about the right dosage to start. Is 100mg of testosterone a week enough?

This article will discuss TRT, the importance of optimal T levels, the factors influencing TRT dosage, and how to determine what is best for you.

Is 100mg of Testosterone a Week Enough

How Does TRT Work?

Testosterone is a hormone primarily produced in the testicles of males and ovaries of females, although the adrenal glands also secrete small amounts. It is a crucial hormone for sexual development and function and maintaining bone density, muscle mass, and red blood cell production.1

TRT is usually prescribed to men who produce less testosterone, a condition known as hypogonadism. This can cause many symptoms, including low libido, erectile dysfunction, fatigue, depression, and loss of muscle mass and strength.

TRT can be administered in several forms, including injections, patches, gels, and pellets implanted under the skin. The goal of TRT is to restore testosterone levels to a normal range and improve the symptoms of hypogonadism.2

The Importance of Optimal Testosterone Levels

Is 100mg of testosterone a week enough? Is it optimal? Optimal testosterone levels are important for overall health and well-being. 

Low testosterone levels can lead to a variety of symptoms, including:3

  • Decreased sex drive
  • Erectile dysfunction
  • Decreased muscle mass and strength
  • Increased body fat
  • Decreased bone density
  • Depression

High T Levels

Is 100mg of testosterone a week enough, or is it too high? High testosterone levels can lead to a range of symptoms in men. 

These can include:4

  • Acne
  • Excessive body hair
  • High sex drive
  • Aggressive or risk-taking behaviors
  • Headaches
  • Insomnia
  • Mood swings
  • Unexplained weight gain
  • Infertility
  • Heart or liver problems
  • Prostate enlargement

Optimal testosterone levels have numerous benefits and help overcome all the negative effects that result from low and high levels of T. 

By improving sexual function, muscle mass, bone density, and mood and decreasing the risk of several medical conditions, restoring T levels to optimal can increase overall well-being.

What Are Normal Levels?

Is 100mg of testosterone a week enough to maintain normal levels? Normal levels of testosterone in men vary depending on age and health status. 

Generally, 300-1000 ng/dL are normal, but levels can decrease as men age.

Dosage of Testosterone in TRT

When undergoing TRT, it is important to determine the appropriate dosage of testosterone for the individual. 

Several factors can affect the dosage, such as:

  • Age
  • Weight 
  • Health status
  • Method of administration
  • Response to treatment

Pros and Cons of TRT Administration

With numerous testosterone formulations available, choosing the appropriate dosage and delivery method can be challenging for clinicians.
Below is the list of different testosterone formulations approved by the United States Food and Drug Administration, with the pros and cons of each application.5

Buccal

The optimal dose is 1 tablet (30mg) every twelve hours. It mimics circadian testosterone rhythm and can be quickly reversed. 

Gum disorders such as irritation, inflammation, and gingivitis can occur. The dosage frequency is the primary downside.

Nasal

The optimal dose is 1 actuation in each nostril 3 times a day (33 mg/day). It’s non-invasive and non-transferable. Rhinorrhea, nosebleeds, and nasal discomfort can occur. The dosage frequency is the primary downside.

Subdermal

The optimal dose is 150–450 mg implanted SQ every 3–6 months. The dosing frequency is low, and there is no potential for transfer; thus, compliance is improved. 

It requires local anesthesia and surgical incision. Fibrosis, bleeding, infection at the insertion site, and pellet extrusion may occur.

Transdermal Patch

The optimal dose is 4mg nightly.  It mimics the circadian rhythm of testosterone and is easy to apply. 

However, you cannot use the same patch site for 7 days. Skin blistering, pruritus, and irritation can occur.

Gel: AndroGel®

The optimal dose is 50 mg applied to shoulders, upper arms, or abdomen once daily in the morning. Several areas are available for application, and it’s easy to apply. 

There’s a risk of transferring to others. An increase in PSA levels, acne, and application site reactions can occur.

Gel: Fortesta®

The optimal dose is 40 mg applied to the thighs once daily in the morning. The metered dose pump allows 10 mg adjustments. It is easy to apply. 

There’s a risk of transferring to others. Mild to moderate skin reactions at the application site can occur.

Gel: Testim®

The optimal dose is 50 mg applied to the shoulders or upper arms once daily in the morning. It’s easy to apply but comes with a transfer risk. Skin reactions at the application site may occur.

Gel: Vogelxo®

The optimal dose is 50 mg applied to the shoulders or upper arms once daily at the same time. It causes less skin irritation than transdermal patches, but there’s a risk of transfer to others. Skin irritation at the site of application can occur.

Solution: Axiron®

The optimal dose is 60 mg applied to the underarms once daily in the morning. Using an applicator decreases the risk of transfer to others. 

There’s still potential for the risk of transfer to others. Skin irritation at the site of application and nasopharyngitis can occur.

IM Testosterone Cypionate

The optimal dose is 50–400 mg every 2–4 weeks. It requires less frequent dosing than topical applications. Fluctuations in mood or libido should be avoided if soy hypersensitivity is present. Side effects include inflammation and pain at the injection site.

IM Testosterone Enanthate

The optimal dose is 50-400 mg every 2-4 weeks. It requires less frequent dosing than topical applications. Side effects include inflammation and pain at the injection site.

IM Testosterone Undecanoate

The optimal dosing schedule is 750 mg once, 750 mg 4 weeks later, then 750 mg every 10 weeks. It requires the least frequent dosing of all IM formulations. 

It also requires monitoring patients 30 minutes post-dose. Anaphylaxis, inflammation, and pain at the injection site can occur.

Testosterone replacement therapy aims to restore serum testosterone levels to the normal range, 300 ng/dL and 1000 ng/dL.

What to Know About Dosages

Typically, healthcare providers recommend the smallest possible dose and gradually work up as needed while closely monitoring your testosterone levels to ensure you receive the appropriate amount for your body. 

Adjustments to your dosage may be made based on side effects you experience or changes in your hormone levels over time.

Is 100mg of Testosterone a Week Enough?

What Is the Best Course of Action for You?

Is 100mg of testosterone a week enough to make a difference for you? The decision on what TRT option is best for an individual depends on several factors. These factors include the patient’s medical history, current health status, lifestyle, personal preferences, and treatment goals. 

A qualified healthcare provider can evaluate these factors and help determine the most appropriate TRT option for the individual. It is also important for patients to be actively involved in the decision-making process, ask questions, and express concerns to their healthcare provider. 

Additionally, patients should have regular follow-up visits with their healthcare provider to monitor their response to treatment and make any necessary adjustments.

Immortal Male and TRT

At Immortal Male, we believe every man deserves to live life to the fullest. As a concierge online TRT clinic, we are committed to helping men achieve optimal testosterone levels through individualized treatment plans.

Our team of healthcare professionals can help determine the right dosage for you, monitor your testosterone levels, and manage any potential side effects. If you have concerns about low testosterone levels or are interested in TRT, reach out to us today.

Journal of Clinical Endocrinology and Metabolism

Stephanie T. Page, John K. Amory, F. DuBois Bowman, Bradley D. Anawalt, Alvin M. Matsumoto, William J. Bremner, J. Lisa Tenover, Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T, The Journal of Clinical Endocrinology & Metabolism, Volume 90, Issue 3, 1 March 2005, Pages 1502–1510, https://doi.org/10.1210/jc.2004-1933B)