Does TRT
Increase Lifespan?

Does TRT Increase Lifespan?

What is testosterone replacement therapy (TRT)? Does TRT increase lifespan? Read on to learn more about the benefits of TRT.

Table of Contents

How Can TRT Help Individuals?

Testosterone replacement therapy (TRT) helps alleviate symptoms associated with low testosterone levels, such as fatigue, low libido, and mood swings. With TRT’s many benefits, people may also wonder – does TRT increase lifespan?

In this article, we’ll explore the potential impact of TRT on lifespan, the benefits and risks of this treatment, and the potential long-term benefits of testosterone replacement therapy.
Does TRT Increase Lifespan

How Is Testosterone Administered?

Testosterone is the primary sex hormone responsible for the development of sexual characteristics and reproductive function in men. 
TRT can be administered in different forms, including:
  • Injections
  • Skin patches
  • Gels
  • Pellets implanted under the skin
  • Buccal systems
TRT aims to increase testosterone levels to normal levels to help alleviate symptoms associated with low testosterone, such as reduced sex drive, erectile dysfunction, fatigue, and mood changes.
TRT is typically prescribed to men diagnosed with hypogonadism, a medical condition in which the body doesn’t produce enough testosterone.1

Benefits of TRT

For those with hypogonadism, the benefits of TRT can include the following:2

  • Improved libido and sexual function
  • Increased muscle mass and strength
  • Improved bone density
  • Increased energy levels and reduced fatigue
  • Improved mood and cognitive function
  • Reduced risk of depression and anxiety
  • Improved insulin sensitivity and blood sugar control
  • Reduced risk of cardiovascular disease
  • Improved quality of life

Does TRT Increase Lifespan?

With the multiple benefits that TRT offers, does TRT increase lifespan as well? While TRT hasn’t been proven to specifically increase lifespan, with added benefits such as reduced risk of cardiovascular disease and reduced risks of depression, it does help remedy certain issues that can decrease lifespan.

Potential Side Effects of TRT

While TRT may have numerous benefits, it’s also important to understand the potential risks associated with this treatment. 

Some of the potential side effects of TRT include:3

  • Acne and oily skin
  • Breast enlargement (gynecomastia)
  • Testicular shrinkage
  • Increased risk of blood clots
  • Increased risk of prostate cancer
  • Sleep apnea or the worsening of existing sleep apnea
  • Increased risk of heart disease and stroke
  • Mood swings and irritability
  • Increased red blood cell count

The Impact of TRT on Lifespan

The impact of TRT on lifespan has been studied extensively, but the results have been inconclusive. Some studies have suggested that TRT may enhance lifespan, while others have shown no significant effect.
A study revealed that men with low testosterone levels who received TRT had a lower risk of all-cause mortality than those who did not receive TRT.4However, there is also evidence that TRT did not improve lifespan in men with low testosterone levels.5
Therefore, further research is required to fully understand the relationship between TRT and lifespan. The conflicting findings may be due to differences in study design, population characteristics, and treatment protocols.

How Can TRT Help?

Regardless of the debate over the impact of TRT on lifespan, it is widely accepted that TRT increases quality of life, and furthermore, that testosterone has health benefits for men with low hormone levels.

The Potential Long-Term Benefits of TRT

One of these significant long-term benefits is improved cardiovascular health. TRT has been found to improve cardiovascular risk factors, such as blood pressure, cholesterol levels, and insulin resistance, reducing cardiovascular disease risk overall.6
Another potential benefit of TRT on lifespan is a reduced risk of diabetes and obesity-related diseases. TRT may help to reduce the risk of Type 2 diabetes and obesity-related diseases, such as nonalcoholic fatty liver disease.7

Other Benefits of TRT

Additionally, TRT has several other common benefits, including improved energy levels, increased muscle mass, improved sexual function, improved bone density, decreased body fat, and improved mood.
While the benefits of TRT on lifespan may vary among individuals and studies, TRT has shown potential for improving overall health and longevity in men with low testosterone levels.

Is 100mg of Testosterone a Week Enough?

Now that we’ve already weighed the benefits, risks, and impact of testosterone replacement therapy on lifespan, it’s important to consider the appropriate dosage for TRT.

The appropriate dosage and delivery method for testosterone therapy can be challenging to determine. There are various formulations available, each with its advantages and disadvantages. 

What Is the Recommended Dosage?

Testosterone replacement therapy aims to restore serum testosterone levels to the normal range of 300 ng/dL and 1000 ng/dL.8
According to the FDA, the recommended starting dose is between 50 to 400 mg IM every two to four weeks. The Endocrine Society Clinical Practice Guidelines suggest an alternative of either 75 to 100 mg IM weekly or 150 to 200 mg IM every two weeks as well.8

Finding the Appropriate Dosage of TRT

Therefore, 100mg of testosterone per week may be enough for some men undergoing TRT, but the appropriate dosage should be determined with the guidance of a healthcare provider.
Generally, healthcare providers recommend the smallest possible dose and gradually work up as needed while closely monitoring your testosterone levels. Dosage adjustments may be made based on side effects or changes in hormone levels over time.
Does TRT Increase Lifespan?

Contact Immortal Male Today

TRT has been shown to be an effective treatment for men with low testosterone levels. This treatment can have numerous benefits, including improved libido, energy levels, and muscle mass. Additionally, TRT may positively impact lifespan and reduce the risk of age-related conditions. 

However, discussing the potential risks and benefits of TRT with your doctor before starting this treatment is important. It is also imperative to determine the right dosage under the guidance of your healthcare provider before starting TRT.

Reach Out to Immortal Male

If you have been dealing with low testosterone levels, we can help. Immortal Male is a trusted testosterone replacement therapy clinic specializing in optimizing testosterone levels. We will work with you to help you achieve optimal health and vitality if you suffer from hypogonadism. 

Our personalized TRT treatment plans are designed to improve your quality of life. We use science-based solutions and offer the highest level of care and support. Don’t hesitate to contact us today to learn more about how we can help you live life to the fullest.

Journal of Clinical Endocrinology and Metabolism

Stephanie T. Page, John K. Amory, F. DuBois Bowman, Bradley D. Anawalt, Alvin M. Matsumoto, William J. Bremner, J. Lisa Tenover, Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T, The Journal of Clinical Endocrinology & Metabolism, Volume 90, Issue 3, 1 March 2005, Pages 1502–1510,