What is the
Downside of TRT?

What is the Downside of TRT?

TRT helps thousands of men to feel like their best, most powerful selves. But what is the downside of TRT? Read on to find out.

Table of Contents

What is TRT?

Testosterone replacement therapy (TRT) is used to increase hormone testosterone levels in men. TRT treats men with low testosterone, known as hypogonadism or “low-T.” While TRT can benefit some people, it carries certain risks and side effects that must be considered before starting treatment. But what is the downside of TRT?

TRT can provide benefits such as increased energy, improved libido, and better mood. However, it’s not a miracle cure; its effects are mild in most cases, and it may take several months to see any noticeable change.

In this article, we will explore some of the drawbacks of testosterone replacement therapy. We will seek to answer the question “what is the downside of TRT” below.

What is the Downside of TRT

What is the Downside of TRT?

While it has many benefits, TRT does have its drawbacks. Some of these potential drawbacks include sleep apnea, skin reactions, and prostate health. All of these factors should be considered before starting testosterone replacement therapy.

Downsides of TRT

Some answers to the question “what is the downside of TRT” are detailed below.

Sleep Apnea

What is the downside of TRT in terms of sleep? Sleep apnea is a sleep disorder where breathing repeatedly stops and starts. It disrupts sleep and can have severe health consequences. One downside of TRT is that it can worsen sleep apnea for some patients.

TRT increases testosterone levels, which can cause the muscles in your airway to relax more during sleep. This relaxation makes the airway more prone to collapse, increasing the severity of sleep apnea.1

Untreated or worsened sleep apnea can lead to significant health problems. These include high blood pressure, heart disease, stroke, and type 2 diabetes. Disrupted sleep can also cause daytime fatigue. This affects your ability to concentrate and perform daily tasks.

Skin Reactions and Acne

What is the downside of TRT when it comes to the skin? Increased testosterone levels may cause excess oil production in the skin. This can clog pores, leading to acne breakouts.2
The severity and prevalence of skin reactions vary. Some people may have mild reactions, while others could face more severe acne or skin issues. Some patients may also experience rashes, itching, or redness due to the therapy.

Mitigating Potential Risks

To manage TRT-induced acne and skin issues, it’s important to practice good skincare. This includes washing your face twice a day with a gentle cleanser and moisturizing regularly. Additionally, it may be helpful to speak with your doctor about topical treatments or oral medications that can reduce inflammation and improve skin health.

Impact on Prostate Health

What is the downside of TRT for prostate health? Benign prostatic hyperplasia (BPH) is a noncancerous prostate gland enlargement. It’s common in older men. It can cause symptoms like frequent urination, difficulty starting or stopping urination, weak urine flow, and the sensation of incomplete bladder emptying. BPH can impact your quality of life and may require medical intervention.

One downside of TRT is its potential to stimulate BPH growth. Increased testosterone levels can cause the prostate gland to enlarge, worsening BPH symptoms. It’s essential to monitor prostate health closely when undergoing TRT, especially for those already experiencing BPH.3
TRT may also pose risks for those with existing prostate cancer. Testosterone can fuel the growth of prostate cancer cells, potentially accelerating cancer progression.

Other Potential Risks and Side Effects

In addition to the issues mentioned earlier, the downsides of TRT can also include the following:
  • Increased risk of blood clots: TRT can raise the number of red blood cells, thickening the blood. This increased thickness may lead to blood clots, which can cause life-threatening conditions like deep vein thrombosis, pulmonary embolism, or stroke.
  • Mood changes and aggression: High testosterone levels can lead to mood swings, aggression, or irritability. These side effects are typically mild and go away when TRT is stopped.
  • Gynecomastia: Gynecomastia is a condition where male breasts become enlarged. TRT may worsen its symptoms in some patients. Although it’s not a life-threatening issue, gynecomastia can be uncomfortable and may affect self-confidence.
  • Reduced sperm production and fertility: TRT can suppress natural testosterone production, leading to reduced sperm production and, consequently, decreased fertility. If you plan to have children, discuss this potential downside of TRT with your healthcare provider.

Who Should Not Undergo TRT?

TRT may not be suitable for everyone. Some patients should avoid TRT due to:
  • Known or suspected prostate cancer
  • Severe sleep apnea or other breathing disorders
  • History of congestive heart failure, stroke, or thrombosis
  • History of substance abuse or addiction
  • Taking certain medications that interact negatively with TRT
  • Under the age of 18

Age and TRT

Older patients may face higher risks when undergoing TRT. As men age, prostate issues and cardiovascular risks can increase. If you’re over the age of 45 and considering TRT, make sure to discuss your specific risks with your doctor.

Monitoring and Managing TRT Risks

Monitoring your health closely while undergoing therapy is essential. Schedule routine appointments with your healthcare provider to assess your response to TRT and monitor potential side effects. Lab tests, such as blood tests to check testosterone levels, prostate-specific antigens (PSA), and blood cell counts, can help track your progress and identify any emerging risks.
Your doctor may be able to fine-tune your TRT regimen to minimize side effects while still offering the desired benefits. This balancing act can make TRT a viable option for some patients.

Is TRT Still Worth It?

Despite the potential risks, TRT can be an effective treatment for many men. The therapy can significantly improve energy levels, muscle mass, mood, and sexual performance for men with low testosterone levels. It may be worth considering TRT as a means to improve your health and quality of life.4

What is the Downside of TRT?

TRT at Immortal Male

If you find yourself asking questions like “what is the downside of TRT?” Immortal Male has the answers. At Immortal Male, we strive to make testosterone replacement therapy (TRT) safe and convenient. Our online TRT clinic offers telehealth consultations with doctors specializing in TRT. We also provide testing and prescription services – all from the comfort of your own home.
We understand the downside of TRT, which is why we take every precaution to ensure our patient’s safety and well-being. We require careful medical assessments for each patient before starting the therapy, and we closely monitor progress throughout. Our team is available to answer any questions or concerns you may have about TRT.

Contact Immortal Male Today

Ultimately, we believe that TRT can be a powerful tool when used correctly – and with proper caution – to improve the quality of life for men with low testosterone levels.

If you’re wondering “what is the downside of TRT,” contact us today, and let us help you take control of your health.

Journal of Clinical Endocrinology and Metabolism

Stephanie T. Page, John K. Amory, F. DuBois Bowman, Bradley D. Anawalt, Alvin M. Matsumoto, William J. Bremner, J. Lisa Tenover, Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T, The Journal of Clinical Endocrinology & Metabolism, Volume 90, Issue 3, 1 March 2005, Pages 1502–1510, https://doi.org/10.1210/jc.2004-1933B)