Revitalizing Midlife: Should a
50 Year Old Man Take Testosterone?

Revitalizing Midlife: Should a 50 Year Old Man Take Testosterone?

Should a 50 year old man take testosterone? Read on to learn how testosterone supplementation with Immortal Male can help.

Table of Contents

Introduction to Testosterone Replacement Therapy

Should a 50 year old man take testosterone? As men age, a gradual decline in testosterone levels is natural. This is referred to as andropause, or late-onset hypogonadism. But what does this mean for the vitality and health of a 50-year-old man?

In this article, we explore the benefits of TRT, from muscle mass enhancement to libido improvement. We will also look into the potential risks, which may include impacts on cardiovascular and prostate health.
Should a 50 year old man take testosterone?

Benefits of Testosterone Supplementation for a 50-Year-Old Man

So, should a 50 year old man take testosterone? Testosterone therapy can benefit some aspects of well-being in men experiencing testosterone declines. However, individual responses to testosterone can vary. Not all men will see the same benefits.

There can also be risks and side effects associated with testosterone supplementation, so it should only be undertaken under the supervision of a healthcare provider. 

But here are some of the potential benefits of using testosterone:1

Increased Muscle Mass

Testosterone is crucial for muscle development. Supplementation can aid in increasing lean body mass and strength. This might benefit those experiencing age-related muscle loss.

Improved Energy Levels

Many men report an increase in energy levels when they start testosterone supplementation. If low energy is due to low testosterone, TRT can help. Improved energy levels can help men in many aspects of life, such as work, exercise, and other activities.

Improved Libido

Testosterone also plays a critical role in male sexual drive. Men with lower levels of testosterone might experience reduced libido. Testosterone therapy can help improve this.

Bone Health

Testosterone is important for maintaining bone density. This can become important as men age and their risk of osteoporosis increases.

Mood and Quality of Life

Some research suggests that testosterone can influence mood and well-being.2 Men with low testosterone levels sometimes report feelings of depression or irritability. This may be improved with supplementation.

Cognitive Abilities

Some research suggests a correlation between testosterone levels and cognitive abilities. This can include memory and spatial ability.3 However, some men might experience cognitive improvement from supplementation.
Testosterone levels decrease as men age, but not all men will experience symptoms related to low testosterone. The decision to use testosterone supplements should be based on a combination of blood tests and symptoms.

Potential Risks or Side Effects of Using Testosterone Supplementation

If you’re wondering, “should a 50 year old man take testosterone?”, it’s also important to consider the risks. TRT may come with some risks that may exacerbate existing issues from the aging process. 

Some potential risks and side effects include:4

Cardiovascular Risks

There has been some controversy about the risk of cardiovascular events associated with testosterone therapy. Some studies suggest an increased risk, while others don’t find a significant association.
However, testosterone therapy can increase the production of red blood cells. This can lead to conditions like blood clots or stroke in some people.5

Prostate Health

Testosterone can stimulate the growth of the prostate. This may lead to problems such as increased urinary symptoms.

Skin Reactions

Testosterone is often administered through the skin by using patches or gels. Some men can have skin reactions at the site of application, including itching, blistering, or soreness.

Sleep Apnea

TRT may also worsen sleep apnea.6 This is a condition where there are repeated stops and starts in breathing during sleep. If you have sleep apnea, be sure to discuss TRT with your doctor before starting treatment.


Testosterone can stimulate the bone marrow to produce more red blood cells. This can lead to a condition called polycythemia.7 Polycythemia may also increase the risk of blood clots and stroke.

Hormonal Imbalances

Testosterone supplementation can impact other hormone levels. This is true for those involved in the production of sperm. This could impact fertility in men still interested in having children.

Psychiatric Effects

Some men may experience mood or mental health symptoms, such as:
  • Mood swings
  • Increased aggression
  • Other changes in mood or behavior
Other potential side effects can include fluid retention, acne, or breast enlargement. Regular follow-up is crucial to reduce potential risks.

Factors That Determine If You Are Suitable for Testosterone Therapy

The decision to start TRT should be based on several factors. It is best done under the guidance of a healthcare provider. 

Here are some factors that may determine if a 50-year-old man would be a suitable candidate for testosterone therapy:

  • Testosterone levels. You may consider testosterone therapy if you have levels below 300 ng/dL.
  • If hypogonadism symptoms are present and have a negative impact on quality of life.
  • Certain health conditions that might negate being able to start TRT, such as cancer, heart issues, or elevated red blood cell counts. 
  • Lifestyle should also be considered before initiating testosterone therapy. 
  • If side effects occur after treatment has started, then TRT may need to be reassessed.
  • Personal and family medical history might influence the decision to start testosterone therapy.
The decision to start testosterone therapy is a collaborative effort. It takes place between you and your healthcare provider. The potential benefits should be weighed against potential risks.

Health Impacts of the Natural Decline of Testosterone

Testosterone levels decrease as men age. The rate of decline varies among individuals, but it often begins around the age of 30 and continues throughout life. By the time a man reaches 50, testosterone levels may be lower than they were in his youth.
So, should a 50 year old man take testosterone? Well, decreased testosterone can impact a man’s health in several ways including:
  • Reduced muscle mass and strength
  • Decreased bone density
  • Increased body fat
  • Reduced libido
  • Lowered energy levels
  • Decreased mood and cognitive function
Testosterone supplementation can help improve some of these symptoms, especially if they are due to hypogonadism.

Potential Treatment Options Before TRT

Before initiating TRT, consider other factors that could be contributing to symptoms. Lifestyle changes can also improve these symptoms. These changes can include:
  • Increasing physical activity
  • Improving diet
  • Managing stress
Also, some men may not experience any symptoms despite having lower testosterone levels. For these men, TRT may not be necessary.

Potential Psychological and Cognitive Benefits and Risks Associated with Testosterone Supplementation

Should a 50 year old man take testosterone? Well, testosterone plays a role in various cognitive and psychological processes in men. 

Here are some of the cognitive benefits and risks associated with TRT:

Potential Benefits

Testosterone supplementation might improve mood and enhance the sense of well-being in men who have low testosterone levels and depressive symptoms.

Testosterone therapy can also help improve cognitive function in men with low testosterone levels.

Potential Risks

Testosterone is sometimes associated with aggression and mood swings at higher dosage levels.
High doses of testosterone have been linked to psychiatric effects such as mania or psychosis in rare cases. However, these effects are more often associated with misuse of testosterone.
Not all men with low testosterone will experience cognitive or mood-related symptoms. Also, other factors can influence mood and cognitive function, including:
  • General health
  • Sleep
  • Diet
  • Exercise
  • Mental health conditions
You should consider TRT as part of a comprehensive health strategy. This treatment is best overseen by a healthcare provider.

What to Consider Before Starting TRT

If you’re wondering, “should a 50 year old man take testosterone,” there are several things to consider. There are various lifestyle modifications and alternative treatments that can help improve symptoms. 

Often, these should be the first line of intervention before considering testosterone therapy.

Here are a few key recommendations:
  • Get regular exercise, such as resistance and high-intensity interval training.
  • Eat a healthy diet. Certain nutrients (like zinc and vitamin D) are also important for testosterone production.
  • Get adequate sleep.
  • Learn stress management. Techniques such as mindfulness and yoga can help.
  • Moderate alcohol consumption.
  • Avoid illicit substances.
  • Maintain a healthy weight.
  • Consider underlying medical conditions
If these lifestyle changes are not effective in managing symptoms, then it might be appropriate to consider testosterone therapy.
It’s also worth considering that not all symptoms are necessarily related to testosterone levels. The healthcare providers with Immortal Male can help determine the cause and appropriate treatment.

Potential Interactions Between Testosterone Supplementation and Common Medications Used by 50-Year-Old Men

Many people are on various medications, especially as they age. Testosterone therapy can interact with several types of medications.8
Therefore, if you’re deciding, “should a 50 year old man take testosterone,” here are a few interactions to consider:

Blood Pressure Medications

Testosterone can cause salt and water retention. This might increase blood pressure in some men. This could mean adjustments in the dosage of blood pressure medications. Regular monitoring of blood pressure is recommended for men taking testosterone.

Cholesterol-Lowering Drugs (Statins)

Testosterone could impact cholesterol levels. This might alter the effects of cholesterol-lowering drugs. Men taking both testosterone and statins should have their cholesterol levels monitored on a regular basis.

Anticoagulants (Blood Thinners)

Testosterone could increase the risk of blood clotting. This is often relevant for men taking anticoagulant drugs.9

Diabetes Medications

Testosterone can influence glucose metabolism. This might impact blood sugar levels. Men with diabetes who are taking testosterone should check their blood sugar levels closely.
These are only a few potential interactions. Not every man will experience these. So, should a 50 year old man take testosterone? The answer to this can depend on the specific medications and doses used.

Speak to Your Doctor First

Discuss all medications and supplements with a healthcare provider before starting testosterone therapy. The potential benefits of testosterone therapy should always be weighed against potential risks. This includes medication interactions.

Long-Term Effects of Testosterone Supplementation

It’s important to know the long-term effects when starting TRT. Long-term testosterone supplementation can have both benefits and risks for health and well-being. Here are some of the benefits and risks:

Potential Benefits

Long-term testosterone therapy can provide ongoing relief from symptoms of low testosterone. It can also help maintain bone density in men with low testosterone. This can reduce the risk of fractures over the long term.
Testosterone can help maintain muscle mass and strength over the long-term as well. This can reduce the risk of falls and frailty in older men.

Potential Risks

As mentioned, some studies suggest a potential increased risk of cardiovascular events with testosterone therapy. This is important to keep in mind with long-term TRT usage.

Monitoring and Follow-Up

Due to the potential risks associated with TRT, regular follow-up is important. Here are some helpful recommendations:
  • Regular testing of testosterone levels can ensure that levels are in the desired range.
  • Regular prostate exams are often recommended to track prostate health.
  • Because testosterone can stimulate the production of red blood cells, regular checking of hematocrit (the proportion of red blood cells in the blood) is important. This could catch any excessive increases that could worsen the risk of blood clots.
  • Regular monitoring of cardiovascular health is also recommended.
  • In some cases, regular bone density tests might be recommended.
  • Regular check-ins about symptoms and side effects are also important.
You should base the decision to use long-term testosterone therapy on careful consideration of the benefits and risks.
Should a 50 year old man take testosterone?

How Can Immortal Male Help Men of All Ages Get Testosterone Replacement Therapy?

Should a 50 year old man take testosterone? At Immortal Male, we’re focused on helping men of any age address and combat symptoms of low testosterone with TRT.

We offer easy access to testosterone replacement therapy and a team of certified doctors and professionals. Our services offer you:

  • At-home assessment and testing to determine if testosterone therapy is right for you.
  • Consultation with a team of certified and professional healthcare providers.
  • As many provider visits as needed
Get access to convenient, high quality care in your own home with Immortal Male. We also offer:
  • Simple and effective at-home testing
  • Fast and discreet delivery
  • Certified doctors and specialists

Get in Touch With Our Team Today

Feel energized and more confident with testosterone replacement therapy at Immortal Male. To find out the answer to “should a 50 year old man take testosterone?”, call today at 1 (512) 764-1351 or visit

Journal of Clinical Endocrinology and Metabolism

Stephanie T. Page, John K. Amory, F. DuBois Bowman, Bradley D. Anawalt, Alvin M. Matsumoto, William J. Bremner, J. Lisa Tenover, Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T, The Journal of Clinical Endocrinology & Metabolism, Volume 90, Issue 3, 1 March 2005, Pages 1502–1510,