What Happens When
You Get Off of TRT?

What Happens When You Get Off of TRT?

Learn about what happens when you get off of TRT and how to ensure a successful transition in this comprehensive article.

Table of Contents

What IsTRT?

Testosterone replacement therapy (TRT) is a medical treatment used to address low levels of testosterone in the body. TRT is effective in increasing muscle mass, bone density, and libido. But what happens when you get off of TRT?

In this article, we will explore what happens when you get off of TRT and the steps to take for a successful transition.
What happens when you get off of TRT?

What Is TRT Used For?

TRT can help alleviate symptoms associated with low testosterone, also known as low T,  levels in men, also known as hypogonadism. This treatment involves the administration of synthetic testosterone, usually through injections, skin patches, gels, or pellets implanted under the skin.

Starting around age thirty, testosterone production in men begins to decrease by 1%–2% each year. Low testosterone levels can lead to a range of symptoms, including reduced libido, erectile dysfunction, fatigue, muscle loss, weight gain, and mood changes.1

By administering testosterone, TRT can help restore testosterone levels to a normal range. Research shows that TRT can increase libido, relieve erectile dysfunction, and improve sexual satisfaction.2

What Happens When You Get off of TRT?

Prolonged testosterone replacement therapy can prevent the body from producing its own testosterone and start depending on the external source. 
What happens when you get off of TRT results in the body no longer having this external source of testosterone. This can lead to changes in hormone levels, causing physical and emotional withdrawal symptoms.

Physical Symptoms

Discontinuing TRT can cause a number of physical symptoms, including:3

  • Decreased muscle mass
  • Decreased bone density
  • Decreased libido
  • Decreased erectile function
  • Decreased bladder wall thickness
  • Fatigue
  • Weight gain
These symptoms can be uncomfortable, and it may take some time for the body to adjust to the lower levels of testosterone.

Emotional Symptoms

Emotional symptoms are another result of what happens when you get off of TRT. Some men may experience the following: 
  • Anxiety
  • Depression
  • Irritability
  • Mood swings
These emotional symptoms can be challenging to deal with, and it may take time for the body to adjust to the lower levels of testosterone.

How Long Does It Take for Hormone Levels to Return to Normal After Stopping TRT?

The time it takes for hormone levels to return to normal after stopping TRT varies from person to person. Some factors include the length of time on TRT, the dosage of testosterone administered, and age.

Average Timeframe for Hormone Levels to Regulate

Generally, it can take several weeks to several months for hormone levels to return to pre-TRT levels. Testosterone levels may drop below normal levels, which is typically what happens when you get off of TRT. But over time, the body should resume its natural production of testosterone.

If you are considering stopping TRT, it is important to talk to your healthcare provider about the potential risks and benefits. You and your doctor can work together to develop a plan for tapering off the medication and monitoring your hormone levels.

Long-Term Health Risks Related to Discontinuing TRT

There is limited research on the long-term health risks associated with what happens when you get off of TRT. Nonetheless, as with treatments for many other health conditions, there are still potential risks and side effects when stopping.

One potential risk associated with what happens when you get off of TRT is the rebound effect, where testosterone levels drop below normal after discontinuing TRT. 
This can lead to symptoms such as fatigue, reduced libido, depression, and loss of muscle mass. In some cases, this can persist for several months.

Additional Risks

Another risk is decreased bone density. One study found that while bone mineral density greatly improved in men who consistently used TRT, it decreased again after stopping. This is an important factor to keep in mind when considering discontinuing TRT.4
Note that since testosterone is such a powerful hormone for men, the body and mind will not feel the same after stopping testosterone intake. 

Steps to Ensure a Successful Transition and Maintain Healthy Hormonal Balance

While various physical and emotional side effects are the result of what happens when you get off of TRT, there are ways to reduce their severity. 

Several steps can be taken to ensure a successful transition from TRT and maintain a healthy hormonal balance. 

These include:
  • Working with a healthcare provider: A healthcare provider can help manage hormone levels and monitor for any potential complications.
  • Gradually reducing TRT dosage: Gradually reducing TRT dosage can help minimize withdrawal symptoms and allow the body to adjust to lower hormone levels.
  • Making healthy lifestyle changes: Lifestyle changes like regular exercise and a healthy diet can help support overall health and hormone balance.
  • Considering alternative treatments: Alternative treatments, such as natural supplements or hormone replacement therapy, may be an option for managing hormone levels.

Lifestyle Changes to Help Adjust to Lower Hormone Levels

There are several lifestyle changes that can help adjust to lower hormone levels after discontinuing TRT: 
  • Regular exercise can help increase testosterone levels naturally.
  • A diet rich in fruits, vegetables, lean protein, and healthy fats can help support overall health and hormone balance.
  • Stress can impact hormone levels, so finding ways to manage stress, such as meditation or yoga, is important.
  • Getting enough sleep can improve overall health and hormone balance.
  • Certain supplements like DHEA or zinc may help support hormone balance.

Is It Recommended to Take TRT for Life?

The length of TRT depends on the individual and their situation. Some men, especially those with hypogonadism, may require long-term TRT to manage low T levels. 
Hypogonadism is a medical condition in which the testicles do not function properly and cannot produce enough testosterone. Thus, medical professionals may recommend life-long TRT for men with hypogonadism.
Others may be able to stop taking TRT after a period of time. It is important to work with a healthcare provider to discuss what happens when you get off of TRT and determine the best course of treatment for managing low testosterone levels.

Signs to Avoid Getting Off of TRT

There are certain warning signs that may indicate a person should avoid getting off of TRT. These include:
  • Long-term TRT can cause greater difficulty adjusting to lower hormone levels.
  • Depression or anxiety can cause more severe emotional symptoms after discontinuing TRT.
  • Cardiovascular disease can increase the risk of cardiovascular complications after stopping TRT.
  • Osteoporosis or low bone density history can increase the risk for bone complications after discontinuing TRT.
What happens when you get off of TRT?

Immortal Male and TRT

At Immortal Male, we understand that low testosterone levels can significantly impact your well-being. 
Immortal Male’s online clinic aims to help address low T levels and improve your quality of life. Our experienced healthcare providers will work closely with you to create a customized treatment plan. 

We Can Help

If you’re experiencing symptoms of low testosterone, don’t hesitate to reach out to us. And if you feel like stopping TRT, we’re here to answer your questions about what happens when you get off of TRT and help you determine if it is the right choice for you.
What happens when you get off of TRT can lead to a number of physical and emotional symptoms, as well as potential long-term health risks. Proper management and lifestyle changes make it possible to transition from TRT successfully and maintain a healthy hormonal balance. 

Reach Out to Immortal Male for TRT Related Questions

It is essential to work with a healthcare provider to determine the best course of treatment for managing low testosterone levels and ensuring long-term health. 

Reach out to Immortal Male today to learn more.

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Journal of Clinical Endocrinology and Metabolism

Stephanie T. Page, John K. Amory, F. DuBois Bowman, Bradley D. Anawalt, Alvin M. Matsumoto, William J. Bremner, J. Lisa Tenover, Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T, The Journal of Clinical Endocrinology & Metabolism, Volume 90, Issue 3, 1 March 2005, Pages 1502–1510, https://doi.org/10.1210/jc.2004-1933B)